Lipin 1 (LPIN1) Mouse Monoclonal Antibody [Clone ID: OTI8F10]
USD 436.00
Specifications
Product Data | |
Clone Name | OTI8F10 |
Applications | IHC, WB |
Recommended Dilution | WB 1:500, IHC 1:150 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human LPIN1 (NP_663731) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 98.5 kDa |
Gene Name | lipin 1 |
Database Link | |
Background | This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined. [provided by RefSeq, May 2012] |
Synonyms | PAP1 |
Reference Data |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF805972 | Carrier-free (glycerol/BSA-free) LPIN1 mouse monoclonal antibody, clone OTI8F10 (formerly 8F10) |
USD 600.00 |
|
TA805972 | LPIN1 mouse monoclonal antibody, clone OTI8F10 (formerly 8F10) |
USD 447.00 |
|
TA805972AM | LPIN1 mouse monoclonal antibody, clone OTI8F10 (formerly 8F10), Biotinylated |
USD 509.00 |
|
TA805972BM | LPIN1 mouse monoclonal antibody, clone OTI8F10 (formerly 8F10), HRP conjugated |
USD 509.00 |
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