HDAC9 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI7G2]

CAT#: TA805328BM

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HDAC9 mouse monoclonal antibody, clone OTI7G2 (formerly 7G2), HRP conjugated



  View other "OTI7G2" antibodies (4)

USD 509.00


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Size
    • 100 ul


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Specifications

Product Data
Clone Name OTI7G2
Applications IHC, WB
Recommended Dilution WB 1:2000, IHC 1:150
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 181-460 of human HDAC9 (NP_055522) produced in E.coli.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation HRP
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 65.7 kDa
Gene Name histone deacetylase 9
Background Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined. [provided by RefSeq, Jul 2008]
Synonyms HD7; HD7b; HD9; HDAC; HDAC7; HDAC7B; HDAC9B; HDAC9FL; HDRP; MITR
Reference Data
Protein Families Druggable Genome, Transcription Factors

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