GLI1 Mouse Monoclonal Antibody [Clone ID: OTI4E2]

CAT#: TA803967

GLI1 mouse monoclonal antibody, clone OTI4E2 (formerly 4E2)

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 Product Datasheet for 'TA803967'

USD 350


Availability*
In Stock

Size
    • 100 ul

Specifications

Product Data
Clone Name OTI4E2
Applications WB, IHC
Recommend Dilution WB 1:2000, IHC 1:150,
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 755-1106 of human GLI1 (NP_005260) produced in E.coli.
Isotype IgG1
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids by affinity chromatography
Predicted Protein Size 117.7 kDa
Gene Name GLI family zinc finger 1
Background This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009].
Synonyms GLI
Reference Data
Protein Families Stem cell relevant signaling - DSL/Notch pathway, ES Cell Differentiation/IPS, Adult stem cells, Cancer stem cells, Embryonic stem cells, Transcription Factors, Druggable Genome
Protein Pathways Hedgehog signaling pathway, Pathways in cancer, Basal cell carcinoma
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.