CD68 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1E6]

CAT#: TA803288BM

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CD68 mouse monoclonal antibody, clone OTI1E6 (formerly 1E6), HRP conjugated



  View other "OTI1E6" antibodies (4)

USD 509.00


Availability*
2 Weeks

Size
    • 100 ul


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Specifications

Product Data
Clone Name OTI1E6
Applications IHC, WB
Recommended Dilution WB 1:2000
Reactivities Human
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 22-319 of human CD68 (NP_001242)produced in SF9 cell.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation HRP
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name CD68 molecule
Background This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]
Synonyms GP110; LAMP4; SCARD1
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Lysosome

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