CD63 Mouse Monoclonal Antibody [Clone ID: OTI2G6]
Specifications
Product Data | |
Clone Name | OTI2G6 |
Applications | FC, IHC, WB |
Recommended Dilution | WB 1:2000, IHC 1:150 |
Reactivity | Human |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human CD63 (NP_001771) produced in HEK293T cell. |
Formulation | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 25.5 kDa |
Gene Name | CD63 molecule |
Database Link | |
Background | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012] |
Synonyms | LAMP-3; ME491; MLA1; OMA81H; TSPAN30 |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Lysosome |
Citations (3)
The use of this Antibodies has been cited in the following citations: |
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Targeting Exosomal EBV-LMP1 Transfer and miR-203 Expression via the NF-κB Pathway: The Therapeutic Role of Aspirin in NPC
,Zuo, L;Xie, Y;Tang, J;Xin, S;Liu, L;Zhang, S;Yan, Q;Zhu, F;Lu, J;,
Mol Ther Nucleic Acids 2019
,PubMed ID 31265948
[CD63]
|
Exosomal cyclophilin A as a novel noninvasive biomarker for Epstein-Barr virus associated nasopharyngeal carcinoma
,Liu, L;Zuo, L;Yang, J;Xin, S;Zhang, J;Zhou, J;Li, G;Tang, J;Lu, J;,
Cancer Med 2019
,PubMed ID 31063269
[CD63]
|
Mechanisms of the effectiveness of lipid nanoparticle formulations loaded with anti-tubercular drugs combinations toward overcoming drug bioavailability in tuberculosis
,Banerjee, S;Roy, S;Bhaumik, KN;Pillai, J;,
J Drug Target 2019
,PubMed ID 31035816
[CD63]
|
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Other Versions
SKU | Description | Size | Price |
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CF802751 | Carrier-free (BSA/glycerol-free) CD63 mouse monoclonal antibody, clone OTI2G6 (formerly 2G6) |
USD 495.00 |
|
TA802751AM | CD63 mouse monoclonal antibody,clone 2G6, Biotinylated |
USD 420.00 |
|
TA802751BM | CD63 mouse monoclonal antibody,clone 2G6, HRP conjugated |
USD 420.00 |
|
TA802751S | CD63 mouse monoclonal antibody, clone OTI2G6 (formerly 2G6) |
USD 169.00 |