CD63 Mouse Monoclonal Antibody [Clone ID: OTI2G6]
CD63 mouse monoclonal antibody, clone OTI2G6 (formerly 2G6)
Product Datasheet for 'TA802751'
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|Applications||WB, IHC, FC|
|Recommend Dilution||WB 1:2000, IHC 1:150,|
|Immunogen||Full length human recombinant protein of human CD63 (NP_001771) produced in HEK293T cell.|
|Formulation||PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purification||Purified from mouse ascites fluids by affinity chromatography|
|Predicted Protein Size||25.5 kDa|
|Gene Name||CD63 molecule|
|Background||The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012].|
|Protein Families||Transmembrane, Druggable Genome|