Neuraminidase (NEU1) Mouse Monoclonal Antibody [Clone ID: OTI3D4]

CAT#: TA801727S

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NEU1 mouse monoclonal antibody, clone OTI3D4 (formerly 3D4)



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USD 186.00


Availability*
In Stock

Size
    • 30 ul


Specifications

Product Data
Clone Name OTI3D4
Applications IHC, WB
Recommended Dilution WB 1:2000, IHC 1:150
Reactivity Human
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 48-315 of human NEU1 (NP_000425)produced in E.coli.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 40.2 kDa
Gene Name neuraminidase 1 (lysosomal sialidase)
Background The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity. [provided by RefSeq, Jul 2008]
Synonyms NANH; NEU; SIAL1
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Lysosome, Other glycan degradation, Sphingolipid metabolism

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