Dicer (DICER1) Mouse Monoclonal Antibody [Clone ID: OTI1G8]

SKU TA801644

DICER1 mouse monoclonal antibody, clone OTI1G8 (formerly 1G8)

Product Data

• Clone Name: OTI1G8
• Application: IHC, WB
• Recommended Dilution: IHC 1:150
• Reactivity: Human, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 1666-1922 of human DICER1 (NP_085124) produced in E.coli.
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 218.5 kDa
• Gene Name: dicer 1, ribonuclease III
• Database Link:
  NP_085124
  Q9UPY3
• Background: This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep
• Synonyms: DCR1; Dicer; Dicer1e; HERNA; K12H4.8-LIKE; MNG1; RMSE2

Reference Data

• Protein Families: Druggable Genome