APE1 (APEX1) Mouse Monoclonal Antibody [Clone ID: OTI6E10]

CAT#: TA800334

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APEX1 mouse monoclonal antibody, clone OTI6E10 (formerly 6E10)



  View other "OTI6E10" antibodies (4)

Get 29% off any Over-Expression Cell Lysate, a validated WB control, with any Ab purchase. Use code “OEL29“. View details.

USD 379.00


Availability*
In Stock

Size
    • 100 ul


Specifications

Product Data
Clone Name OTI6E10
Applications FC, IF, IHC, WB
Recommended Dilution WB 1:1000, IHC 1:150, IF 1:100, FLOW 1:100
Reactivity Human, Mouse, Rat
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 1-242 of human APEX1 (NP_001632) produced in E.coli.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 35.4 kDa
Gene Name apurinic/apyrimidinic endodeoxyribonuclease 1
Background Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq]
Synonyms APE; APE1; APEN; APEX; APX; HAP1; REF1
Reference Data
Protein Families Druggable Genome, Stem cell - Pluripotency, Transcription Factors
Protein Pathways Base excision repair

Other Versions

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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