Methionine Aminopeptidase 2 (METAP2) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1F6]

CAT#: TA800289BM

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METAP2 mouse monoclonal antibody,clone 1F6, HRP conjugated



  View other "OTI1F6" antibodies (4)

USD 509.00


Availability*
5 Days

Size
    • 100 ul


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Specifications

Product Data
Clone Name OTI1F6
Applications FC, IF, IHC, WB
Recommended Dilution WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 2-212 of human METAP2 (NP_006829) produced in E.coli.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation HRP
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 52.7 kDa
Gene Name methionyl aminopeptidase 2
Background This gene is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. [provided by RefSeq]
Synonyms MAP2; MNPEP; p67eIF2
Reference Data
Protein Families Druggable Genome, Protease

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