TMS1 (PYCARD) Mouse Monoclonal Antibody [Clone ID: OTI2A7]

CAT#: TA800080

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PYCARD (TMS1) mouse monoclonal antibody, clone OTI2A7 (formerly 2A7)

Size: 30 ul 100 ul

Formulation: Standard Carrier-Free

Conjugation: Unconjugated Biotin HRP



  View other "OTI2A7" antibodies (4)

USD 447.00

In Stock*

Size
    • 100 ul

Frequently bought together (3)
Recombinant protein of human PYD and CARD domain containing (PYCARD), transcript variant 1
    • 100 ug

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Transient overexpression lysate of PYD and CARD domain containing (PYCARD), transcript variant 1
    • 100 ug

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beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
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Specifications

Product Data
Clone Name OTI2A7
Applications FC, IHC, WB
Recommended Dilution WB 1:500~2000, IHC 1:150, FLOW 1:100
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human PYCARD (NP_037390) produced in E.coli.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 21.4 kDa
Gene Name PYD and CARD domain containing
Background This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Synonyms ASC; CARD5; TMS; TMS-1; TMS1
Reference Data
Protein Families Druggable Genome
Protein Pathways Cytosolic DNA-sensing pathway, NOD-like receptor signaling pathway

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