Cytokeratin 19 (KRT19) Biotinylated Mouse Monoclonal Detection Antibody (Biotin conjugated) [Clone ID: OTI5H6]

SKU TA700573

KRT19 biotinylated mouse monoclonal antibody, clone OTI5H6

Product Data

• Clone Name: OTI5H6
• Application: ELISA
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment of human KRT19 (NP_002267) produced in E.coli.
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Shipping: Blue Ice
• Predicted Protein Size: 43.9 kDa
• Gene Name: keratin 19
• Database Link:
  NP_002267
  P08727
• Background: Keratin-19 (KRT19) also known as keratin, type I cytoskeletal 19, cytokeratin-19 (CK-19), or CYFRA 21-1, is a 40 kDa protein that in humans is encoded by the KRT19 gene. Keratin 19 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 19 is a type I keratin. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. KRT19 is the most used marker for the RT-PCR-mediated detection of tumor cells disseminated in lymph nodes, peripheral blood, and bone marrow of breast cancer patients. There is a positive correlation between higher expression of KRT19 in some kind of cancers and worse patient survival, where it serves as a diagnostic or prognostic biomarker.
• Synonyms: CK19; K1CS; K19
• Matched ELISA Pair: TA600573

Reference Data