P cadherin(CDH3) Mouse Monoclonal Antibody [Clone ID: OTI2D5]

CAT#: TA506403

CDH3 (P cadherin) mouse monoclonal antibody, clone OTI2D5 (formerly 2D5)

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 Product Datasheet for 'TA506403'

USD 379


Availability*
In Stock

Size
    • 100 ul

Specifications

Product Data
Clone Name OTI2D5
Applications WB, IHC, IF
Recommend Dilution WB 1:4000, IHC 1:150, IF 1:100,
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human CDH3(NP_001784) produced in HEK293T cell.
Isotype IgG2a
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids by affinity chromatography
Predicted Protein Size 88.8 kDa
Gene Name cadherin 3
Background This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy. [provided by RefSeq, Jul 2008].
Synonyms CDHP|HJMD|PCAD
Reference Data
Protein Families Transmembrane, Druggable Genome
Protein Pathways Cell adhesion molecules (CAMs)
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