PSMB9 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2B6]

CAT#: TA504392AM

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PSMB9 (Proteasome 20S LMP2) mouse monoclonal antibody, clone OTI2B6 (formerly 2B6), Biotinylated



USD 462.00


Availability*
2 Weeks

Size
    • 100 ul


Specifications

Product Data
Clone Name OTI2B6
Applications IHC, WB
Recommended Dilution WB 1:500~2000, IHC 1:150
Reactivities Human, Monkey, Mouse, Rat, Dog
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 21-219 of human PSMB9(NP_002791) produced in E.coli.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Biotin
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 23.1 kDa
Gene Name proteasome 20S subunit beta 9
Background The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 1 (proteasome beta 6 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. [provided by RefSeq]
Synonyms beta1i; LMP2; PSMB6i; RING12
Reference Data
Protein Families Druggable Genome, Protease
Protein Pathways Proteasome
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