JAB1 (COPS5) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI2B12]
CAT#: TA504344BM
COPS5 (JAB1) mouse monoclonal antibody, clone OTI2B12 (formerly 2B12), HRP conjugated
Conjugation: Unconjugated Biotin
USD 867.00
USD 436.00
Specifications
Product Data | |
Clone Name | OTI2B12 |
Applications | IF, IHC, WB |
Recommended Dilution | WB 1:2000, IHC 1:150, IF 1:100 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human COPS5(NP_006828) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol. |
Concentration | 0.5 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | HRP |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 37.4 kDa |
Gene Name | COP9 signalosome subunit 5 |
Database Link | |
Background | The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. [provided by RefSeq] |
Synonyms | CSN5; JAB1; MOV-34; SGN5 |
Reference Data | |
Protein Families | Druggable Genome, Protease, Transcription Factors |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF504344 | Carrier-free (BSA/glycerol-free) COPS5 mouse monoclonal antibody, clone OTI2B12 (formerly 2B12) |
USD 600.00 |
|
TA504344 | COPS5 (JAB1) mouse monoclonal antibody, clone OTI2B12 (formerly 2B12) |
USD 447.00 |
|
TA504344AM | COPS5 (JAB1) mouse monoclonal antibody, clone OTI2B12 (formerly 2B12), Biotinylated |
USD 509.00 |
|
TA504344S | COPS5 (JAB1) mouse monoclonal antibody, clone OTI2B12 (formerly 2B12) |
USD 200.00 |
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