COASY Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI3B3]

SKU TA503344BM

COASY mouse monoclonal antibody, clone OTI3B3 (formerly 3B3), HRP conjugated

Product Data

• Clone Name: OTI3B3
• Application: FC, IF, IHC, WB
• Recommended Dilution: WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
• Reactivity: Human, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human COASY(NP_079509) produced in HEK293T cell.
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: HRP
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 62.1 kDa
• Gene Name: Coenzyme A synthase
• Database Link:
  NP_079509
  Q13057
• Background: Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. COASY is a bifunctional enzyme that catalyzes the 2 last steps in CoA synthesis. These activities are performed by 2 separate enzymes, phosphopantetheine adenylyltransferase (PPAT; EC 2.7.7.3) and dephospho-CoA kinase (DPCK; EC 2.7.1.24), in prokaryotes (Daugherty et al., 2002 [PubMed 11923312]). [supplied by OMIM]
• Synonyms: DPCK; NBIA6; NBP; pOV-2; PPAT; UKR1

Reference Data

• Protein Pathways: Metabolic pathways, Pantothenate and CoA biosynthesis