BAIAP2 Mouse Monoclonal Antibody [Clone ID: OTI8G8]

CAT#: TA503323

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BAIAP2 mouse monoclonal antibody, clone OTI8G8 (formerly 8G8)



Special Offer: Try sample size of this antibody at $99/€99. Use code "TrueSample".

USD 417.00


Availability*
In Stock

Size
    • 100 ul


Specifications

Product Data
Clone Name OTI8G8
Applications IF, IHC, WB
Recommended Dilution WB 1:2000, IHC 1:150, IF 1:100
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human BAIAP2(NP_006331) produced in HEK293 cell.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.65 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 57.3 kDa
Gene Name BAR/IMD domain containing adaptor protein 2
Background The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Synonyms BAP2; FLAF3; IRSP53
Reference Data
Protein Families Druggable Genome
Protein Pathways Adherens junction, Regulation of actin cytoskeleton
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