IKB zeta(NFKBIZ) Mouse Monoclonal Antibody [Clone ID: OTI1E8]

CAT#: TA502768

NFKBIZ mouse monoclonal antibody, clone OTI1E8 (formerly 1E8)

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 Product Datasheet for 'TA502768'

USD 379.00

In Stock

    • 100 ul

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Product Data
Clone Name OTI1E8
Applications WB, FC
Recommend Dilution WB 1:500, FLOW 1:100
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human NFKBIZ (NP_113607) produced in E.coli.
Isotype IgG1
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.58 mg/ml
Purification Purified from mouse ascites fluids by affinity chromatography
Predicted Protein Size 77.9 kDa
Gene Name NFKB inhibitor zeta
Background This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Reference Data
Protein Families Druggable Genome
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