NUMB Mouse Monoclonal Antibody [Clone ID: OTI1A7]

SKU TA501614

NUMB mouse monoclonal antibody, clone OTI1A7 (formerly 1A7)

Product Data

• Clone Name: OTI1A7
• Application: FC, IF, WB
• Recommended Dilution: WB 1:2000, IF 1:100, FLOW 1:100
• Reactivity: Human, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human NUMB (NP_003735) produced in HEK293T cell.
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.6 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 69.3 kDa
• Gene Name: NUMB endocytic adaptor protein
• Database Link:
  NP_003735
  P49757
• Background: The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene.
• Synonyms: C14orf41; c14_5527; S171

Reference Data

• Protein Pathways: Notch signaling pathway