L1CAM Mouse Monoclonal Antibody [Clone ID: OTI1A8]

CAT#: TA501437

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L1CAM mouse monoclonal antibody, clone OTI1A8 (formerly 1A8)


 Product Datasheet for 'TA501437'

  View other "OTI1A8" antibodies (2)

USD 360.00


Availability*
In Stock

Size
    • 100 ul


Specifications

Product Data
Clone Name OTI1A8
Applications FC, IF, WB
Recommend Dilution WB 1:2000, IF 1:100, FLOW 1:100
Reactivity Human
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Full length human recombinant protein of human L1CAM (NP_000416) produced in HEK293T cell.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids by affinity chromatography
Predicted Protein Size 137.8 kDa
Gene Name L1 cell adhesion molecule
Background The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant. [provided by RefSeq]
Synonyms CAML1; CD171; HSAS; HSAS1; MASA; MIC5; N-CAM-L1; N-CAML1; NCAM-L1; S10; SPG1
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Axon guidance, Cell adhesion molecules (CAMs)

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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