PKA R2 (PRKAR2A) Mouse Monoclonal Antibody [Clone ID: OTI1F8]

CAT#: TA501146

PRKAR2A (PKA R2 ) mouse monoclonal antibody, clone OTI1F8 (formerly 1F8)


 Product Datasheet for 'TA501146'

  View other "OTI1F8" antibodies (2)

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USD 360.00


Availability*
In Stock

Size
    • 100 ul


Specifications

Product Data
Clone Name OTI1F8
Applications FC, IF, IHC, WB
Recommend Dilution WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human PRKAR2A (NP_004148) produced in HEK293T cell.
Isotype IgG1
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.74 mg/ml
Purification Purified from mouse ascites fluids by affinity chromatography
Predicted Protein Size 45.3 kDa
Gene Name protein kinase cAMP-dependent type II regulatory subunit alpha
Background cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER). [provided by RefSeq].
Synonyms PKR2; PRKAR2
Reference Data
Protein Families Druggable Genome
Protein Pathways Apoptosis, Insulin signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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