XRCC1 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2D8]

SKU TA500886AM

XRCC1 mouse monoclonal antibody, clone 2D8, Biotinylated

Product Data

• Clone Name: OTI2D8
• Application: FC, IHC, WB
• Recommended Dilution: WB 1:2000, IHC 1:50, FLOW 1:100
• Reactivity: Human, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human XRCC1 (NP_006288) produced in HEK293T cell.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 69.3 kDa
• Gene Name: X-ray repair cross complementing 1
• Database Link:
  NP_006288
  P18887
• Background: The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq]
• Synonyms: RCC

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Base excision repair