DHFR Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI3A11]

CAT#: TA500517BM

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DHFR mouse monoclonal antibody, Clone 3A11, HRP conjugated



USD 462.00


Availability*
5 Days

Size
    • 100 ul


Specifications

Product Data
Clone Name OTI3A11
Applications IHC, WB
Recommended Dilution WB: 1:200 - 1:1000 IHC 1:50
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Full-length protein expressed in 293T cell transfected with human DHFR expression vector
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation HRP
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 21.5 kDa
Gene Name dihydrofolate reductase
Background Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia.
Synonyms DHFRP1; DYR
Reference Data
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Folate biosynthesis, Metabolic pathways, One carbon pool by folate
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