VMAT2 (SLC18A2) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI10C11]

SKU TA500463AM

Anti-SLC18A2 (VMAT2) mouse monoclonal antibody, clone OTI10C11 (formerly 10C11), Biotinylated

Product Data

• Clone Name: OTI10C11
• Application: IHC, WB
• Recommended Dilution: WB 1:500 IHC 1:50
• Reactivity: Human, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full-length protein expressed in 293T cell transfected with human SLC18A2 expression vector
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 55.7 kDa
• Gene Name: solute carrier family 18 member A2
• Database Link:
  NP_003045
  Q05940
• Background: The vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles,using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and Xenazine.
• Synonyms: SVAT; SVMT; VAT2; VMAT2

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Parkinson's disease