FOXA2 Mouse Monoclonal Antibody [Clone ID: OTI3C10]

SKU TA500073S

Anti-FOXA2 mouse monoclonal antibody, clone OTI3C10 (formerly 3C10)

Product Data

• Clone Name: OTI3C10
• Application: FC, IF, IHC, WB
• Recommended Dilution: WB: 1:1000; IHC: 1:50; IF: 1:50-1:100; Flow 1:1,000
• Reactivity: Human, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant protein expressed in E.coli corresponding to amino acids 300-458 of human FOXA2
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 48.1 kDa
• Gene Name: forkhead box A2
• Database Link:
  NP_710141
  Q9Y261
• Background: FOXA2 is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene
• Synonyms: HNF3B; TCF3B

Reference Data

• Protein Families: Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors
• Protein Pathways: Maturity onset diabetes of the young