Periostin (POSTN) Mouse Monoclonal Antibody [Clone ID: OTI1A1]

SKU TA500070S

Periostin (Periostin) mouse monoclonal antibody, clone OTI1A1 (formerly 1A1)

Product Data

• Clone Name: OTI1A1
• Application: IF, WB
• Recommended Dilution: WB 1:500, IF 1:100
• Reactivity: Human, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgM
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 1-230 of human periostin (NP_006466) produced in E.coli.
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 93.2 kDa
• Gene Name: periostin
• Database Link:
  NP_006466
  Q15063
• Background: Periostin is a disulfide linked 90 kDa, 811 amino acid protein originally isolated as a osteoblast-specific factor that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Additionally, periostin expression has previously been shown to be significantly increased by both transforming growth factor beta 1(TGF beta 1) and bone morphogenetic protein (BMP2). Periostin mRNA is expressed in the developing mouse embryonic and fetal heart, and that it is localized to the endocardial cushions that ultimately divide the primitive heart tube into a four-chambered heart. Abnormal expression of periostin is also linked to angiogenesis and metastatsis in epithelial tumors.
• Synonyms: OSF-2; OSF2; PDLPOSTN; PN

Reference Data

• Protein Families: Druggable Genome, Secreted Protein