WAVE 1 (WASF1) Rabbit Monoclonal Antibody [Clone ID: R03-5K1]
| Product Data | |
| Clone Name | R03-5K1 |
|---|---|
| Application | WB |
| Recommended Dilution | WB: 1/1000-1/5000 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | Recombinant protein of human WAVE 1 |
| Buffer | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Concentration | lot specific |
| Purification | Affinity Purified |
| Conjugation | Unconjugated |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Stability | 1 year |
| Shipping | Blue Ice |
| Predicted Protein Size | Calculated MW: 62 kDa; Observed MW: 90 kDa |
| Gene Name | WAS protein family member 1 |
| Database Link | |
| Background | Swiss-Prot Acc.Q92558.Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex . As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes . |
| Synonyms | FLJ31482; KIAA0269; OTTHUMP00000016990; SCAR1; WAVE; WAVE1 |
| Reference Data | |
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