NFATC1 Rabbit Monoclonal Antibody [Clone ID: R03-6I1]
| Product Data | |
| Clone Name | R03-6I1 |
|---|---|
| Application | WB |
| Recommended Dilution | WB: 1/1000 |
| Reactivity | Human, Mouse |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Ser237 of human NFAT2 (Phosphorylated) |
| Buffer | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Concentration | lot specific |
| Purification | Affinity Purified |
| Conjugation | Unconjugated |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Stability | 1 year |
| Shipping | Blue Ice |
| Predicted Protein Size | Calculated MW: 101 kDa; Observed MW: 101 kDa |
| Database Link | |
| Background | Swiss-Prot Acc.O95644.Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells (PubMed:10358178). Required for osteoclastogenesis and regulates many genes important for osteoclast differentiation and function . |
| Reference Data | |
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