Heme Oxygenase 1 (HMOX1) Rabbit Monoclonal Antibody [Clone ID: R02-6C1]
| Product Data | |
| Clone Name | R02-6C1 |
|---|---|
| Application | IF, IHC, IP, WB |
| Recommended Dilution | WB: 1/1000 IHC: 1/50 ICC/IF: 1/50 IP: 1/20 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | Recombinant protein of mouse Heme Oxygenase 1 |
| Buffer | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Concentration | lot specific |
| Purification | Affinity Purified |
| Conjugation | Unconjugated |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Stability | 1 year |
| Shipping | Blue Ice |
| Predicted Protein Size | Calculated MW: 33 kDa; Observed MW: 33 kDa |
| Gene Name | heme oxygenase 1 |
| Database Link | |
| Background | Swiss-Prot Acc.P09601.Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis. |
| Synonyms | bK286B10; HO; HO-1; HO1; HSP32 |
| Reference Data | |
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