GABARAPL2 Rabbit Monoclonal Antibody [Clone ID: R03-7J2]
| Product Data | |
| Clone Name | R03-7J2 |
|---|---|
| Application | WB |
| Recommended Dilution | WB: 1/1000 |
| Reactivity | Human, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | A synthetic peptide of human GABARAPL2 |
| Buffer | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Concentration | lot specific |
| Purification | Affinity Purified |
| Conjugation | Unconjugated |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Stability | 1 year |
| Shipping | Blue Ice |
| Predicted Protein Size | Calculated MW: 14 kDa; Observed MW: 14 kDa |
| Gene Name | GABA type A receptor associated protein like 2 |
| Database Link | |
| Background | Swiss-Prot Acc.P60520.Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 . Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. |
| Synonyms | ATG8; FLC3A; GATE-16; GATE16; GEF-2; GEF2 |
| Reference Data | |
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