GABARAPL2 Rabbit Monoclonal Antibody [Clone ID: R03-7J2]

CAT#: TA384278

GABARAPL2 Rabbit monoclonal Antibody

Product Images

Western blot analysis of GABARAPL2 in C6, Hela lysates using GABARAPL2 antibody.

Specifications

Product Data

• Clone Name: R03-7J2
• Applications: WB
• Recommended Dilution: WB: 1/1000
• Reactivities: Human, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human GABARAPL2
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 14 kDa; Observed MW: 14 kDa
• Gene Name: GABA type A receptor associated protein like 2
• Database Link:
  Entrez Gene 11345 Human
  UniProt ID P60520
• Background: Swiss-Prot Acc.P60520.Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 . Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.
• Synonyms: ATG8; FLC3A; GATE-16; GATE16; GEF-2; GEF2