Bak (BAK1) Rabbit Monoclonal Antibody [Clone ID: R03-6A8]
| Product Data | |
| Clone Name | R03-6A8 |
|---|---|
| Application | IHC, IP, WB |
| Recommended Dilution | WB: 1/1000 IHC: 1/20 IP: 1/20 |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | A synthetic peptide of human Bak |
| Buffer | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Concentration | lot specific |
| Purification | Affinity Purified |
| Conjugation | Unconjugated |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Stability | 1 year |
| Shipping | Blue Ice |
| Predicted Protein Size | Calculated MW: 23 kDa; Observed MW: 23 kDa |
| Gene Name | BCL2 antagonist/killer 1 |
| Database Link | |
| Background | Swiss-Prot Acc.Q16611.Plays a role in the mitochondrial apoptosic process. Upon arrival of cell death signals, promotes mitochondrial outer membrane (MOM) permeabilization by oligomerizing to form pores within the MOM. This releases apoptogenic factors into the cytosol, including cytochrome c, promoting the activation of caspase 9 which in turn processes and activates the effector caspases. |
| Synonyms | BAK; BAK-LIKE; Bcl2-L-7; BCL2L7; CDN1; MGC3887; MGC117255 |
| Reference Data | |
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