Bak (BAK1) Rabbit Monoclonal Antibody [Clone ID: R03-6A8]

CAT#: TA383804

Bak Rabbit monoclonal Antibody

Product Images

Western blot analysis of Bak in K562, Hela lysates using Bak antibody.

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  Immunohistochemistry analysis of paraffin-embedded Human colon cancer using Bak antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Specifications

Product Data

• Clone Name: R03-6A8
• Applications: IHC, IP, WB
• Recommended Dilution: WB: 1/1000
  IHC: 1/20
  IP: 1/20
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human Bak
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 23 kDa; Observed MW: 23 kDa
• Gene Name: BCL2 antagonist/killer 1
• Database Link:
  Entrez Gene 578 Human
  UniProt ID Q16611
• Background: Swiss-Prot Acc.Q16611.Plays a role in the mitochondrial apoptosic process. Upon arrival of cell death signals, promotes mitochondrial outer membrane (MOM) permeabilization by oligomerizing to form pores within the MOM. This releases apoptogenic factors into the cytosol, including cytochrome c, promoting the activation of caspase 9 which in turn processes and activates the effector caspases.
• Synonyms: BAK; BAK-LIKE; Bcl2-L-7; BCL2L7; CDN1; MGC3887; MGC117255