Annexin A2 (ANXA2) Rabbit Monoclonal Antibody [Clone ID: R09-5C1]
| Product Data | |
| Clone Name | R09-5C1 |
|---|---|
| Application | IF, WB |
| Recommended Dilution | WB: 1/1000 ICC/IF: 1/50 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | A synthetic peptide of human Annexin A2 |
| Buffer | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Concentration | lot specific |
| Purification | Affinity Purified |
| Conjugation | Unconjugated |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Stability | 1 year |
| Shipping | Blue Ice |
| Predicted Protein Size | Calculated MW: 39 kDa; Observed MW: 38 kDa |
| Gene Name | annexin A2 |
| Database Link | |
| Background | Swiss-Prot Acc.P07355.Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9 (PubMed:18799458, PubMed:24808179, PubMed:22848640). |
| Synonyms | Annexin-2; ANX2; ANX2L4; CAL1H; Chromobindin-8; LIP2; LPC2; LPC2D; P36; PAP-IV |
| Reference Data | |
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