CD147 (BSG) Rabbit Polyclonal Antibody

CAT#: TA354245

Rabbit anti CD147/EMMPRIN Polyclonal Antibody

Specifications

Product Data

• Recommended Dilution: WB 0.1-1 µg/ml ELISA N/A IP N/A IHC 2-10 µg/ml FC Not tested
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of full length of human CD147.
• Formulation: This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
• Purification: The Rabbit IgG is purified by Epitope Affinity Purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 27 kDa
• Gene Name: basigin (Ok blood group)
• Database Link:
  NP_001309172
  Entrez Gene 682 Human
  UniProt ID P35613
• Background: CD147 or EMMPRIN (extracellular matrix metalloproteinase inducer) is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. This protein is also a member of the immunoglobulin super-family, it is a 58kDa protein with two immunoglobulin domains that was originally purified from the plasma membrane of the human LX-1 lung carcinoma cell line. CD147 has been localized on the outer surface of tumor cells, where it interacts withfibroblasts to stimulate the expression of matrix metalloproteinases (MMPs). CD147 inhibition has been proposed as a novel strategy in the prevention of cancer invasion and metastasis.
• Synonyms: 5F7; CD147; EMMPRIN; OK; TCSF

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane