COX4 (COX4I1) Rabbit Polyclonal Antibody
Rabbit Polyclonal Anti-COX4I1 Antibody
Product Datasheet for 'TA352009'
|Recommend Dilution||ELISA: 1000-2000, IHC: 10-50|
|Immunogen||Synthetic peptide of human COX4I1|
|Formulation||pH7.4 PBS, 0.05% NaN3, 40% Glyceroln|
|Purification||Antigen affinity purification|
|Gene Name||cytochrome c oxidase subunit 4I1|
|Background||Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it.|
|Synonyms||COX4; COX4-1; COXIV; COX IV-1; COXIV-1|
|Protein Pathways||Alzheimer's disease, Cardiac muscle contraction, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.