NME2 Rabbit Polyclonal Antibody

CAT#: TA351806

Rabbit Polyclonal Anti-NME2 Antibody

Product Images

Gel: 12%SDS-PAGE Lysate: 40 μg Lane 1-7: Hela cells NIH/3T3 cells LNCap cells 293T cells Mouse brain tissue A549 cells Jurkat cells Primary antibody: TA351806 (NME2 Antibody) at dilution 1/300 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 30 seconds

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  Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using TA351806 (NME2 Antibody) at dilution 1/40 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using TA351806 (NME2 Antibody) at dilution 1/40, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1000-5000
  WB positive control: Hela, NIH/3T3, LNCap and 293T cells, Mouse brain tissue, A549 and Jurkat cells
  IHC: 30-150
  Positive control: Human prostate cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human NME2
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 17 kDa
• Gene Name: NME/NM23 nucleoside diphosphate kinase 2
• Database Link:
  NP_002503
  Entrez Gene 18103 MouseEntrez Gene 83782 RatEntrez Gene 4831 Human
  UniProt ID P22392
• Background: Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by NME1) and 'B' (encoded by this gene) isoforms. Multiple alternatively spliced transcript variants have been found for this gene. Read-through transcription from the neighboring upstream gene (NME1) generates naturally-occurring transcripts (NME1-NME2) that encode a fusion protein comprised of sequence sharing identity with each individual gene product.
• Synonyms: NDKB; NDPK-B; NDPKB; NM23-H2; NM23B; PUF

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Metabolic pathways, Purine metabolism, Pyrimidine metabolism