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LARG (ARHGEF12) Rabbit Polyclonal Antibody
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Specifications
| Product Data | |
| Applications | IHC |
| Recommended Dilution | IHC: 50-200 Positive control: Human colon cancer Predicted cell location: Cytoplasm |
| Reactivities | Human, Mouse |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human ARHGEF12 |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Gene Name | Rho guanine nucleotide exchange factor 12 |
| Database Link | |
| Background | Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene. |
| Synonyms | LARG; PRO2792 |
| Reference Data | |
| Protein Pathways | Axon guidance, Regulation of actin cytoskeleton, Vascular smooth muscle contraction |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.