AMZ1 Rabbit Polyclonal Antibody

CAT#: TA350876

Rabbit Polyclonal Anti-AMZ1 Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane 1-2: Human fetal brain tissue Human liver tissue Primary antibody: TA350876 (AMZ1 Antibody) at dilution 1/1000 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 3 minutes

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA350876 (AMZ1 Antibody) at dilution 1/80 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA350876 (AMZ1 Antibody) at dilution 1/80, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Human fetal brain and liver tissue
  IHC: 50-200
  Positive control: Human brain
  Predicted cell location: Cytoplasm
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human AMZ1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 55 kDa
• Gene Name: archaelysin family metallopeptidase 1
• Database Link:
  NP_597720
  Entrez Gene 155185 Human
  UniProt ID Q400G9
• Background: AMZ1 shares sequence similarity with archaeal metalloproteases called archaemetzincins, but it appears to act predominantly as a basic aminopeptidase. Inhibited by the general metalloprotease inhibitors o-phenanthroline and batimastat. Also significantly inhibited by amastatin, which is an inhibitor of aminopeptidases. Not inhibited by 4-(2-aminoethyl)-benzenesulfonyl fluoride, E-64, and TIMPS (tissue inhibitors of metalloproteinases), which are inhibitors of serine, cysteine, and matrix metalloproteases, respectively.
• Synonyms: KIAA1950