BMP9 (GDF2) Rabbit Polyclonal Antibody
Product Data | |
Application | IHC, WB |
---|---|
Recommended Dilution | WB: 200-1000 WB positive control: Mouse heart and liver tissue IHC: 50-200 Positive control: Human ovarian cancer Predicted cell location: Cytoplasm |
Reactivity | Human, Mouse |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human GDF2 |
Buffer | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Predicted Protein Size | 47 kDa |
Gene Name | growth differentiation factor 2 |
Database Link | |
Background | The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein plays a role in the adult liver and in differentiation of cholinergic central nervous system neurons. Mutations in this gene are associated with hereditary hemorrhagic telangiectasia. |
Synonyms | BMP-9; BMP9; HHT5 |
Reference Data | |
Protein Families | Druggable Genome, Secreted Protein |
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