EAAT3 (SLC1A1) Rabbit Polyclonal Antibody

SKU TA350655

Rabbit Polyclonal Anti-GALE Antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: WB: 500-2000; WB positive control: Human placenta tissue and normal liver tissue; IHC: 25-100; Positive control: Human liver cancer; Predicted cell location: Cell membrane and Cytoplasm
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human SLC1A1
• Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 57 kDa
• Gene Name: solute carrier family 1 member 1
• Database Link:
  NP_004161
  P43005
• Background: This gene encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are thought to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect.
• Synonyms: DCBXA; EAAC1; EAAT3; SCZD18

Reference Data

• Protein Families: Druggable Genome, Transmembrane