PDP1 Rabbit Polyclonal Antibody

SKU TA350298

Rabbit Polyclonal Anti-PDP1 Antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: WB: 1000-5000; WB positive control: HepG2 cell lysate; IHC: 150-300; Positive control: Human tonsil; Predicted cell location: Cytoplasm
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human PDP1
• Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 61 kDa
• Gene Name: pyruvate dehyrogenase phosphatase catalytic subunit 1
• Database Link:
  NP_001155251
  Q9P0J1
• Background: Pyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the large pyruvate dehydrogenase complex. Pyruvate dehydrogenase kinases catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits.
• Synonyms: PDH; PDP; PDPC; PPM2A; PPM2C

Reference Data

• Protein Families: Druggable Genome, Phosphatase