Proteasome 20S beta 7 (PSMB7) Rabbit Polyclonal Antibody

CAT#: TA349570

Rabbit Polyclonal Anti-PSMB7 Antibody

Product Images

Gel: 10%SDS-PAGE Lysate: 40 μg Lane 1-4: 293T cells hepG2 cells human testis tissue Human lung cancer tissue Primary antibody: TA349570 (PSMB7 Antibody) at dilution 1/310 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 5 seconds

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  Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA349570 (PSMB7 Antibody) at dilution 1/25 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA349570 (PSMB7 Antibody) at dilution 1/25, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using TA349570 (PSMB7 Antibody) at dilution 1/25 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using TA349570 (PSMB7 Antibody) at dilution 1/25, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: 293T and hepG2 cells, human testis and lung cancer tissue
  IHC: 25-100
  Positive control: Human colon cancer
  Predicted cell location: Cytoplasm and Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human PSMB7
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 30 kDa
• Gene Name: proteasome subunit beta 7
• Database Link:
  NP_002790
  Entrez Gene 19177 MouseEntrez Gene 85492 RatEntrez Gene 5695 Human
  UniProt ID Q99436
• Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. The encoded protein is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon, and proteolytic processing is required to generate a mature subunit. A pseudogene of this gene is located on the long arm of chromosome 14.
• Synonyms: Z

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Proteasome