STAM1 (STAM) Rabbit Polyclonal Antibody

SKU TA349561

Rabbit Polyclonal Anti-STAM Antibody

Product Data

• Application: IHC
• Recommended Dilution: IHC: 50-200; Positive control: Human gasrtic cancer; Predicted cell location: Cytoplasm
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human STAM
• Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: signal transducing adaptor molecule
• Database Link:
  NP_003464
  Q92783
• Background: This gene encodes a member of the signal-transducing adaptor molecule family. These proteins mediate downstream signaling of cytokine receptors and also play a role in ER to Golgi trafficking by interacting with the coat protein II complex. The encoded protein also associates with hepatocyte growth factor-regulated substrate to form the endosomal sorting complex required for transport-0 (ESCRT-0), which sorts ubiquitinated membrane proteins to the ESCRT-1 complex for lysosomal degradation. Alternatively spliced transcript variants have been observed for this gene.
• Synonyms: STAM-1; STAM1

Reference Data

• Protein Pathways: Endocytosis, Jak-STAT signaling pathway