MAD1 (MAD1L1) Rabbit Polyclonal Antibody

CAT#: TA349385

Rabbit Polyclonal Anti-MAD1L1 Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane 1-4: Hela cells 231 cells hepG2 cells Raji cells Primary antibody: TA349385 (MAD1L1 Antibody) at dilution 1/500 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 second

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA349385 (MAD1L1 Antibody) at dilution 1/25 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA349385 (MAD1L1 Antibody) at dilution 1/25, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Hela, 231, hepG2 and Raji cells
  IHC: 25-100
  Positive control: Human brain
  Predicted cell location: Nucleus
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human MAD1L1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 83 kDa
• Gene Name: MAD1 mitotic arrest deficient like 1
• Database Link:
  NP_003541
  Entrez Gene 17120 MouseEntrez Gene 8379 Human
  UniProt ID Q9Y6D9
• Background: MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Three transcript variants encoding the same protein have been found for this gene.
• Synonyms: MAD1; PIG9; TP53I9; TXBP181

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Cell cycle