VEZT Rabbit Polyclonal Antibody

CAT#: TA349097

Rabbit Polyclonal Anti-VEZT Antibody

Product Images

Western blot analysis of VEZT in 293 cell lysate with VEZT antibody at (A) 1 and (B) 2 ug/mL.

• 

  Immunohistochemistry of VEZT in rat kidney tissue with VEZT antibody at 5 ug/mL.

• 

  Immunofluorescence of TRIP12 in rat colon tissue with TRIP12 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: VEZT antibody was raised against a 17 amino acid peptide near the center of human VEZT.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: VEZT antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 63, 68, 78, 81, 83, 86 kDa; Observed: 60
• Gene Name: vezatin, adherens junctions transmembrane protein
• Database Link:
  NP_060069
  Entrez Gene 55591 Human
  UniProt ID Q9HBM0
• Background: Vezatin (VEZT) is a transmembrane protein which localizes to adherens junctions and binds to myosin VIIA and the cadherin-catenins complex (1). Expression of this gene in gastric cancer tissues is decreased due to hypermethylation of the promoter. Expression of this gene may also be inhibited by binding of a specific microRNA to a target sequence in the 3' UTR of the transcripts (2). VEZT has also been shown to be required for morphogenesis of the preimplantation mouse embryo (3).
• Synonyms: VEZATIN