Sex Hormone Binding Globulin (SHBG) Rabbit Polyclonal Antibody

CAT#: TA349087

Rabbit Polyclonal Anti-SHBG Antibody

Product Images

Western blot analysis of SHBG in human liver tissue lysate with SHBG antibody at (A) 1 and (B) 2 ug/mL.

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  Immunofluorescence of SHBG in mouse liver tissue with SHBG antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: SHBG antibody was raised against a 16 amino acid peptide near the center of human SHBG.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: SHBG antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 25, 26, 31, 32, 38, 44 kDa; Observed: 35
• Gene Name: sex hormone binding globulin
• Database Link:
  NP_001031
  Entrez Gene 20415 MouseEntrez Gene 24775 RatEntrez Gene 6462 Human
  UniProt ID P04278
• Background: SHBG is a steroid binding protein that was first described as a plasma protein secreted by the liver and is thought to participate in the regulation of steroid responses. SHBG transports androgens and estrogens in the blood, binding each steroid molecule as a dimer formed from identical or nearly identical monomers (1). Low plasma SHBG levels are associated with obesity, abdominal adiposity, metabolic syndrome, and predict the development of type 2 diabetes (2,3). Polymorphisms in this gene have been associated with polycystic ovary syndrome and type 2 diabetes mellitus (4).
• Synonyms: ABP; SBP; TEBG

Reference Data

• Protein Families: Druggable Genome, Secreted Protein