KLRF1 Rabbit Polyclonal Antibody
Product Data | |
Application | WB |
---|---|
Recommended Dilution | WB |
Reactivity | Human |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | The immunogen for anti-KLRF1 antibody: synthetic peptide directed towards the middle region of human KLRF1. Synthetic peptide located within the following region: QKGSCSNATQYEDTGDLKVNNGTRRNISNKDLCASRSADQTVLCQSEWLK |
Buffer | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Predicted Protein Size | 26 kDa |
Gene Name | killer cell lectin like receptor F1 |
Database Link | |
Background | KLRF1, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on nearly all natural killer (NK) cells and stimulatesTheir cytoxicity and cytokine release (Kuttruff et al., 2009 [PubMed 18922855]). [supplied by OMIM, Oct 2009]. Transcript Variant:This variant (KLRF1-s3) lacks three alternate coding exons that result in a frameshift inThe 3' coding region, compared to variant 1.The encoded isoform (KLRF1-s3) has a distinct C-terminus and is significantly shorter than isoform 1. ##Evidence-Data-START## Transcript exon combination :: AF267245.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support ERS025084, ERS025085 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete onThe 3' end. |
Synonyms | CLEC5C; NKp80 |
Note | Immunogen Sequence Homology: Human: 100% |
Reference Data | |
Protein Families | Transmembrane |
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