IBP160 (AQR) Rabbit Polyclonal Antibody

CAT#: TA338083

Rabbit Polyclonal Anti-AQR Antibody

Product Images

WB Suggested Anti-AQR Antibody; Titration: 1.0 ug/ml; Positive Control: MCF7 Whole Cell AQR is supported by BioGPS gene expression data to be expressed in MCF7

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-AQR antibody is: synthetic peptide directed towards the C-terminal region of Human AQR. Synthetic peptide located within the following region: DTTPSETGATSTPEAIPALSETTPTVVGAVSAPAEANTPQDATSAPEETK
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 171 kDa
• Gene Name: aquarius intron-binding spliceosomal factor
• Database Link:
  NP_055506
  Entrez Gene 9716 Human
  UniProt ID O60306
• Background: AQR is an intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. AQR plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. AQR may act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.
• Synonyms: fSAP164; IBP160
• Note: Immunogen Sequence Homology: Human: 100%; Horse: 79%

Reference Data

• Protein Pathways: Spliceosome