IBP160 (AQR) Rabbit Polyclonal Antibody
Product Data | |
Application | WB |
---|---|
Recommended Dilution | WB |
Reactivity | Human |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | The immunogen for anti-AQR antibody is: synthetic peptide directed towards the C-terminal region of Human AQR. Synthetic peptide located within the following region: DTTPSETGATSTPEAIPALSETTPTVVGAVSAPAEANTPQDATSAPEETK |
Buffer | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Purification | Affinity Purified |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Predicted Protein Size | 171 kDa |
Gene Name | aquarius intron-binding spliceosomal factor |
Database Link | |
Background | AQR is an intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. AQR plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. AQR may act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. |
Synonyms | fSAP164; IBP160 |
Note | Immunogen Sequence Homology: Human: 100%; Horse: 79% |
Reference Data | |
Protein Pathways | Spliceosome |
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