Glucose 6 Phosphate Dehydrogenase (G6PD) Mouse Monoclonal Antibody [Clone ID: 2H7]
Product Data | |
Clone Name | 2H7 |
---|---|
Application | ELISA, FC, IHC, WB |
Recommended Dilution | Flow Cytometry: 1:200-1:400, ELISA: 1:10000, Western Blot: 1:500-1:1000, Immunohistochemistry-Paraffin: 1:200-1:1000, Immunohistochemistry |
Reactivity | Human |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of human Glucose 6 Phosphate Dehydrogenase expressed in E. coli. [UniProt# P11413] |
Buffer | PBS, 0.03% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Concentration | lot specific |
Purification | Ammonium sulfate precipitation |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Predicted Protein Size | 59 kDa |
Gene Name | glucose-6-phosphate dehydrogenase |
Database Link | |
Background | This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. |
Synonyms | G6PD1 |
Note | This Glucose 6 Phosphate Dehydrogenase (2H7) antibody is useful for Western blot, Immunohistochemistry on paraffin-embedded sections, Flow Cytometry and ELISA. |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Glutathione metabolism, Metabolic pathways, Pentose phosphate pathway |
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