ABCG2 Mouse Monoclonal Antibody [Clone ID: 3G8]

CAT#: TA336921

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Mouse Monoclonal ABCG2/CD338 Antibody (3G8)



USD 450.00


Availability*
2 Weeks

Size
    • 100 ul


Other products for "ABCG2"

Specifications

Product Data
Clone Name 3G8
Applications ELISA, FC, IF, IHC, WB
Recommended Dilution WB: 1:500-1:2000, ELISA: 1:10000, FC: 1:200-1:400, IF: 1:200-1:1000, IHC: 1:10-1:500, IHC-P: 1:200-1:1000
Reactivities Human, Mouse, Primate
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Purified recombinant fragment of human ABCG2 expressed in E. coli. [UniProt# Q9UNQ0]
Formulation PBS, 0.03% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Concentration lot specific
Purification Ammonium sulfate precipitation
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 60-70 kDa
Gene Name ATP binding cassette subfamily G member 2 (Junior blood group)
Background The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue.Tissue specificity: Highly expressed in placenta. Low expression in small intestine, liver and colon.
Synonyms ABC15; ABCP; BCRP; BCRP1; BMDP; CD338; CDw338; EST157481; GOUT1; MRX; MXR; MXR-1; MXR1; UAQTL1
Note This ABCG2 (3G8) antibody is useful for Western blot, Immunohistochemistry on paraffin-embedded sections, Immunocytochemistry/Immunofluorescence, Flow Cytometry and ELISA. In WB a dimer can be seen at 60-70 kDa representing ABCG2.
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways ABC transporters
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.