Heme Oxygenase 1 (HMOX1) Rabbit Polyclonal Antibody

CAT#: TA336833

Rabbit Polyclonal HO-1/HMOX1/HSP32 Antibody

Product Images

Immunocytochemistry/Immunofluorescence: HO-1/HMOX1/HSP32 Antibody TA336833 - HepG2 cells with FITC (green). Nuclei were counterstained with DAPI (blue).

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  Immunohistochemistry: HO-1/HMOX1/HSP32 Antibody TA336833 - Analysis of Heme Oxygenase 1 in mouse kidney using DAB with hematoxylin counterstain.

Specifications

Product Data

• Applications: ICC/IF, IHC
• Recommended Dilution: Immunohistochemistry-Paraffin: 1:200, Immunohistochemistry: 1:200, Immunocytochemistry/ Immunofluorescence: 1:100
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: A synthetic peptide made to a C-terminal portion of the human Heme Oxygenase 1 protein (between residues 225-275) [UniProt P09601]
• Formulation: PBS, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: heme oxygenase 1
• Database Link:
  NP_002124
  Entrez Gene 15368 MouseEntrez Gene 24451 RatEntrez Gene 3162 Human
  UniProt ID P09601
• Background: HO-1 (also know as Heme oxygenase-1, HMOX1, HSP32), a member of the heme oxygenase family, is an enzyme for heme catabolism and cleaves heme to form biliverdin. This inducible protein reacts from hypoxia, cytokines, and oxidative stress. HO-1 is itself an antioxidant that protects cells from ROS (reactive oxygen species) by regulating ROS levels. HO-1 has been shown to inhibit the pathogenesis of immune related inflammatory diseases as well as cardiovascular disease (CVD).
• Synonyms: bK286B10; HMOX1D; HO-1; HSP32
• Note: This Heme Oxygenase 1 antibody is useful for Immunocytochemistry/Immunofluorescence and IHC-paraffin embedded sections.

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Porphyrin and chlorophyll metabolism