TFB2M Rabbit Polyclonal Antibody

CAT#: TA335483

Rabbit Polyclonal Anti-TFB2M Antibody

Product Images

WB Suggested Anti-TFB2M Antibody Titration: 1.25 ug/ml; ELISA Titer: 1:312500; Positive Control: Transfected 293T

• 

  Human Intestine

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB, IHC
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for Anti-TFB2M Antibody: synthetic peptide directed towards the N terminal of human TFB2M. Synthetic peptide located within the following region: ECNPGPGILTQALLEAGAKVVALESDKTFIPHLESLGKNLDGKLRVIHCD
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Purification: Protein A purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 45 kDa
• Gene Name: transcription factor B2, mitochondrial
• Database Link:
  NP_071761
  Entrez Gene 64216 Human
  UniProt ID Q9H5Q4
• Background: TFB2M is a S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. It is also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. It stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.
• Synonyms: Hkp1; mtTFB2
• Note: Immunogen Sequence Homology: Horse: 100%; Human: 100%; Rat: 85%; Rabbit: 83%

Reference Data

• Protein Families: Transcription Factors